Polynucleotides are purified DNA fragments, most commonly derived from salmon, which are highly compatible with human skin. They're extensively purified and have an excellent safety profile, having been used in medicine and wound healing for many years.

Most clients see the best results from a course of 2–3 sessions, spaced around 3–4 weeks apart. We'll confirm your recommended plan at consultation based on your skin and goals.

Polynucleotides work with your skin's natural repair process, so results develop gradually. Many clients notice improved hydration within a couple of weeks, with firmness and texture continuing to improve over the following months as collagen production increases.

Results vary by individual, but improvements typically last 6–12 months after a completed course. Maintenance sessions can help keep your results going.

Treatment involves a series of small micro-injections. Most clients describe it as very tolerable, and numbing cream can be applied beforehand to keep you comfortable.

Very little. You may have some small bumps, redness or mild swelling at the injection sites, which usually settle within 24–48 hours. Most clients return to their normal day straight away. We'll give you full aftercare guidance at your appointment.

They're related but work differently. Skin boosters like Profhilo primarily hydrate, while polynucleotides actively stimulate your skin to repair and regenerate. At your consultation we'll recommend which is right for your skin, or whether combining them would suit you best.

Most adults looking to improve skin quality, hydration or early signs of ageing are suitable. Treatment isn't recommended if you're pregnant, breastfeeding, or have a fish allergy (due to the salmon-derived origin). Suitability is always confirmed at consultation.